Aptamer 学术简报 — biosensor — 2026-10-25

自动生成 by RBTX Aptamer Tracker v0.1。 子主题 biosensor：近 14 天 97 篇命中（aptamer 池 177 篇）。

评分公式：composite = 0.45×log(IF) + 0.35×log(cites_velocity) + 0.10×social + 0.10×recency_bonus；满分 100。

#1 [21.7] A bifunctional triblock zwitterionic copolymer combined with gold nanostars for antifouling electrochemical aptasensor to detect chloramphenicol in food samples.

To address the issue of electrochemical sensors being susceptible to fouling interference in complex food matrices, this work proposed a high-performance antifouling aptasensor based on a triblock zwitterionic copolymer and a gold nanostars (Au NSs) conductive substrate. Through precise control over the composition of two zwitterionic monomers [...

#2 [15.6] Triple quenching strategy-based highly sensitive electrochemiluminescence sensor for perfluorooctanoic acid.

Quenching-based electrochemiluminescence (ECL) sensing boasts prominent advantages for trace analysis, while single-mechanism systems have inherent flaws, making the development of efficient synergistic quenching strategies of great practical significance for ultra-trace perfluorooctanoic acid (PFOA) detection. In this work, a zinc-coordinated p...

#3 [15.3] A dual-aptamer colorimetric sensor based on Cu-MOF@PtPdNPs for the highly sensitive detection of MUC1.

The abnormally high expression of MUC1 in various malignant tumors makes it a crucial biomarker for early cancer diagnosis. This study synthesized a Cu-MOF@PtPdNPs nanocomposite exhibiting robust peroxidase-like activity via an in-situ reduction method. By integrating this nanomaterial with a dual-aptamer recognition sandwich strategy, an effici...

#4 [14.5] An Integrated Cascade-Amplified Microfluidic Biosensor for Reconfigurable Profiling of CRC-Associated Faecal Extracellular Vesicle Surface Proteins.

Faecal extracellular vesicles (EVs) provide disease-relevant molecular information for non-invasive colorectal cancer (CRC) analysis. However, sensitive EV surface protein profiling remains challenging because low-abundance targets are obscured by heterogeneous vesicles and complex matrices. Here, an integrated cascade-amplified microfluidic bio...

#5 [14.3] Scaffold RNA Reengineering for a Leakage‐Suppressed CRISPR/Cas12a Cascade System Toward Precise Nucleic Acid Diagnostics

ABSTRACT Amplification‐free CRISPR detection has attracted significant attention for its capacity to circumvent the intricacies of nucleic acid amplification. Yet, the persistent challenge of high background signals remains a critical bottleneck, motivating intensive efforts toward background suppression strategies. Here, we present a 3’‐end DNA...

#6 [13.3] Electrochemical Aptamer-Based Sensors Supporting Real-Time, Seconds-Resolved, Molecular Measurements in Awake, Behaving Rats.

The real-time, in vivo measurement of drugs, metabolites, and biomarkers in awake animals could enable unprecedented insights into metabolic regulation, pharmacokinetics, pharmacodynamics, and behavioral response. In pursuit of this vision, here we demonstrate a subcutaneous electrochemical aptamer-based (EAB) sensor architecture that (i) suppor...

#7 [13.0] A Practical Guide of Choosing and Validating Aptamers for Biosensors.

Aptamers have been reported for hundreds of targets, and for many important analytes, multiple independent selections have yielded distinct sequences. Subsequent truncation, mutation, and chemical modification have further generated numerous variants of the original aptamers. This rapidly expanding sequence space, however, has created a growing ...

#8 [12.9] Digitally Printed Gold Nanoelectronics for Tap-to-Detect Electrochemical Biosensing and Chemical Sensing.

Printed electrochemical sensors offer a promising route toward decentralized diagnostics and environmental monitoring, but their practical use remains constrained by complex electrode fabrication and instrument-dependent readout. Here, we present a tap-to-detect sensing platform that couples digitally printed gold nanoparticle nanoelectronics wi...

#9 [12.8] Aptamer-functionalized solution-gated graphene transistor for rapid detection of trace scandium.

The growing exploitation of rare earth resources has led to the migration and accumulation of Scandium (Sc) within food systems, giving rise to emerging food safety concerns. Conventional techniques for Scandium (III) ions (Sc3+) detection are limited by labor-intensive sample preparation, high instrumentation costs, and poor suitability for rap...

#10 [12.7] PK-Tracker: A Real-Time Bedside Device for Continuous Therapeutic Drug Monitoring.

Medical procedures often require the administration of drugs, whose dosing is typically guided by pharmacodynamic responses rather than direct measurement of concentrations. This limitation largely arises from traditional monitoring procedures that rely on repeated venous sampling followed by laboratory analyses using cumbersome and costly instr...

Methodology