Aptamer 学术简报 — biosensor — 2026-10-19

自动生成 by RBTX Aptamer Tracker v0.1。 子主题 biosensor：近 14 天 97 篇命中（aptamer 池 170 篇）。

评分公式：composite = 0.45×log(IF) + 0.35×log(cites_velocity) + 0.10×social + 0.10×recency_bonus；满分 100。

#1 [20.4] Triple quenching strategy-based highly sensitive electrochemiluminescence sensor for perfluorooctanoic acid.

Quenching-based electrochemiluminescence (ECL) sensing boasts prominent advantages for trace analysis, while single-mechanism systems have inherent flaws, making the development of efficient synergistic quenching strategies of great practical significance for ultra-trace perfluorooctanoic acid (PFOA) detection. In this work, a zinc-coordinated p...

#2 [20.2] A dual-aptamer colorimetric sensor based on Cu-MOF@PtPdNPs for the highly sensitive detection of MUC1.

The abnormally high expression of MUC1 in various malignant tumors makes it a crucial biomarker for early cancer diagnosis. This study synthesized a Cu-MOF@PtPdNPs nanocomposite exhibiting robust peroxidase-like activity via an in-situ reduction method. By integrating this nanomaterial with a dual-aptamer recognition sandwich strategy, an effici...

#3 [13.9] Integrated Antigen–DNA Co‐Detection Using Digital Microfluidics for Improving Diagnostic Accuracy in POCT Analysis

ABSTRACT Simultaneous detection of protein and nucleic acid (NA) provides complementary information essential for accurate analysis of complex samples. Conventional approaches for the analysis of protein and NA typically rely on separate workflows and instruments, limiting the reliability of point‐of‐care testing. Here, we present a digital micr...

#4 [13.9] Integrated Antigen–DNA Co‐Detection Using Digital Microfluidics for Improving Diagnostic Accuracy in POCT Analysis

Simultaneous detection of protein and nucleic acid (NA) provides complementary information essential for accurate analysis of complex samples. Conventional approaches for the analysis of protein and NA typically rely on separate workflows and instruments, limiting the reliability of point-of-care testing. Here, we present a digital microfluidics...

#5 [13.5] Dual-signal fluorescent-colorimetric aptasensor for tobramycin detection in milk based on fluorescent magnetic nanoparticles and AuNPs.

Tobramycin (TOB) is an aminoglycoside antibiotic employed in human and veterinary medicine whose residues in food raise safety concerns. To resolve this issue, we developed a dual-mode aptamer-based sensor for sensitive TOB detection via fluorescence and colorimetric signals. The platform utilizes fluorescent magnetic nanoparticles (FMNs) conjug...

#6 [13.3] A Dual-Lock Activatable Fluorescent Probe Leveraging Tumor Metabolic and Enzymatic Features for Precision Imaging

Abstract Achieving highly sensitive and precise detection and imaging of cancer cells within the body is crucial for providing pathological information support in disease diagnosis and treatment. However, due to the existence of factors such as non-specific activation in local areas, membrane barriers, and the complexity of the intracellular env...

#7 [13.3] A machine learning-optimized bivalent aptasensor based on exonuclease Ⅰ amplification for trace okadaic acid detection

Consumption of okadaic acid (OA)-contaminated seafood endangers human health, highlighting the need for sensitive quantitative detection. Herein, a convenient and highly sensitive bivalent aptasensor was developed for fluorescence detection of OA in aquatic products. The aptasensor was constructed using a bivalent aptamer (B-Apt) as the recognit...

#8 [13.1] PHB/ErGO electrochemical immunosensor for H5N1 serology: Insights into selectivity and inflammation-mediated matrix effects

Reliable electrochemical immunosensing in biological samples requires not only selective molecular recognition but also preservation of analytical performance in complex matrices. Here, a label-free electrochemical immunosensor based on electrochemically reduced graphene oxide (ErGO) and polyhydroxybutyrate (PHB) nanoparticles was developed for ...

#9 [13.1] Fabrication of ultrasensitive ciprofloxacin electrochemical aptasensor based on AuNPs decorated MWCNTs@GO@CS film.

A highly sensitive electrochemical aptasensor (BSA/Apt/MWCNTs@GO@CS/. AuNPs/SPCE) was fabricated for the efficient detection of ciprofloxacin (CIP). The complementary structural and physicochemical properties of MWCNTs and GO provide a conductive and functionalized platform for aptamer immobilization, while the excellent film-forming property of...

#10 [13.1] Employment of mixed aptamers and gold nanobipyramids toward a paper-based aptasensor for simultaneously visual screening and accurate detection of eight sulfonamides.

A variety of sulfonamides (SAs) are extensively utilized in animal husbandry and aquaculture, necessitating the development of high-throughput methods for the rapid screening and accurate determination of multiple, ideally all commonly-applied SAs, in animal-derived foodstuffs. We herein developed a paper-based colorimetric aptasensor for the de...

Methodology