Aptamer 学术简报 — biosensor — 2026-10-18

自动生成 by RBTX Aptamer Tracker v0.1。 子主题 biosensor：近 14 天 87 篇命中（aptamer 池 153 篇）。

评分公式：composite = 0.45×log(IF) + 0.35×log(cites_velocity) + 0.10×social + 0.10×recency_bonus；满分 100。

#1 [21.7] Triple quenching strategy-based highly sensitive electrochemiluminescence sensor for perfluorooctanoic acid.

Quenching-based electrochemiluminescence (ECL) sensing boasts prominent advantages for trace analysis, while single-mechanism systems have inherent flaws, making the development of efficient synergistic quenching strategies of great practical significance for ultra-trace perfluorooctanoic acid (PFOA) detection. In this work, a zinc-coordinated p...

#2 [21.5] A dual-aptamer colorimetric sensor based on Cu-MOF@PtPdNPs for the highly sensitive detection of MUC1.

The abnormally high expression of MUC1 in various malignant tumors makes it a crucial biomarker for early cancer diagnosis. This study synthesized a Cu-MOF@PtPdNPs nanocomposite exhibiting robust peroxidase-like activity via an in-situ reduction method. By integrating this nanomaterial with a dual-aptamer recognition sandwich strategy, an effici...

#3 [14.2] Integrated Antigen–DNA Co‐Detection Using Digital Microfluidics for Improving Diagnostic Accuracy in POCT Analysis

ABSTRACT Simultaneous detection of protein and nucleic acid (NA) provides complementary information essential for accurate analysis of complex samples. Conventional approaches for the analysis of protein and NA typically rely on separate workflows and instruments, limiting the reliability of point‐of‐care testing. Here, we present a digital micr...

#4 [14.2] Integrated Antigen–DNA Co‐Detection Using Digital Microfluidics for Improving Diagnostic Accuracy in POCT Analysis

Simultaneous detection of protein and nucleic acid (NA) provides complementary information essential for accurate analysis of complex samples. Conventional approaches for the analysis of protein and NA typically rely on separate workflows and instruments, limiting the reliability of point-of-care testing. Here, we present a digital microfluidics...

#5 [13.6] A machine learning-optimized bivalent aptasensor based on exonuclease Ⅰ amplification for trace okadaic acid detection

Consumption of okadaic acid (OA)-contaminated seafood endangers human health, highlighting the need for sensitive quantitative detection. Herein, a convenient and highly sensitive bivalent aptasensor was developed for fluorescence detection of OA in aquatic products. The aptasensor was constructed using a bivalent aptamer (B-Apt) as the recognit...

#6 [13.6] Employment of mixed aptamers and gold nanobipyramids toward a paper-based aptasensor for simultaneously visual screening and accurate detection of eight sulfonamides.

A variety of sulfonamides (SAs) are extensively utilized in animal husbandry and aquaculture, necessitating the development of high-throughput methods for the rapid screening and accurate determination of multiple, ideally all commonly-applied SAs, in animal-derived foodstuffs. We herein developed a paper-based colorimetric aptasensor for the de...

#7 [13.3] Synergistic Vacancy-Mediated Adsorption-Activation Strategy and Spatial Confinement Effect for Enhanced Electrochemiluminescence Sensing of Isocarbophos

Abstract Exploring advanced strategies to overcome the sluggish activation kinetics of co-reactants and insufficient radical generation is pivotal for boosting electrochemiluminescence (ECL) sensing performance. Herein, an active radical-enriched ECL sensing platform for the ultrasensitive detection of isocarbophos (ICP) was fabricated by utiliz...

#8 [13.3] Aptamer-Based Fluorescent Assays for Detection of the Host-Response Viral Biomarker 3′-Deoxy-3′,4′-Didehydro-Cytidine

Abstract Improved viral diagnostics are urgently needed to strengthen pandemic preparedness and combat antimicrobial resistance, highlighting the importance of 3′-deoxy-3′,4′-didehydro-cytidine (ddhC), a host-derived, pan-viral biomarker that addresses key limitations of PCR-based diagnostics. Current methods for ddhC measurement rely on liquid ...

#9 [13.3] Fluorescence “Turn-On” Detection of Bisulfite via Specific CN Bond Cleavage: Reactivity, Structure−Property Relationship, and Bioimaging Applications

Abstract It is essential to detect HSO3− for ensuring food safety, preventing environmental pollution, and safeguarding human health. We report a new approach for the fluorescence recognition of HSO3−. The key principle lies in exploiting the specific and irreversible cleavage of the CN bond in the probe’s Schiff base structure by HSO3− to achi...

#10 [13.3] Modular Cell-Surface-to-Solution CRISPR-Cas12a Platform for Wash-Free Quantification of Cell−Surface Proteins on Living Cells

Abstract Cell−surface proteins are important biomarkers for cell phenotyping, disease diagnosis, therapeutic evaluation, and drug screening. However, their quantitative analysis on intact living cells remains challenging because conventional methods often require cell lysis, fixation, repeated washing, extensive sample processing, or bulky instr...

Methodology