Aptamer 学术简报 — biosensor — 2026-10-16

自动生成 by RBTX Aptamer Tracker v0.1。 子主题 biosensor：近 14 天 76 篇命中（aptamer 池 136 篇）。

评分公式：composite = 0.45×log(IF) + 0.35×log(cites_velocity) + 0.10×social + 0.10×recency_bonus；满分 100。

#1 [26.3] Triple quenching strategy-based highly sensitive electrochemiluminescence sensor for perfluorooctanoic acid.

Quenching-based electrochemiluminescence (ECL) sensing boasts prominent advantages for trace analysis, while single-mechanism systems have inherent flaws, making the development of efficient synergistic quenching strategies of great practical significance for ultra-trace perfluorooctanoic acid (PFOA) detection. In this work, a zinc-coordinated p...

#2 [26.1] A dual-aptamer colorimetric sensor based on Cu-MOF@PtPdNPs for the highly sensitive detection of MUC1.

The abnormally high expression of MUC1 in various malignant tumors makes it a crucial biomarker for early cancer diagnosis. This study synthesized a Cu-MOF@PtPdNPs nanocomposite exhibiting robust peroxidase-like activity via an in-situ reduction method. By integrating this nanomaterial with a dual-aptamer recognition sandwich strategy, an effici...

#3 [14.7] Employment of mixed aptamers and gold nanobipyramids toward a paper-based aptasensor for simultaneously visual screening and accurate detection of eight sulfonamides.

A variety of sulfonamides (SAs) are extensively utilized in animal husbandry and aquaculture, necessitating the development of high-throughput methods for the rapid screening and accurate determination of multiple, ideally all commonly-applied SAs, in animal-derived foodstuffs. We herein developed a paper-based colorimetric aptasensor for the de...

#4 [13.5] Anchoring nanozymes on microneedles via nanotemplate sacrificial synthesis for glutathione detection.

Region-specific dysregulation of glutathione (GSH) reflects neuropsychiatric disorders and tumor progression. Microscale precision sampling combined with timely monitoring of GSH provides region-specific molecular information that may aid in disease diagnosis. To enable minimally invasive brain-compatible intraoperative detection of GSH within a...

#5 [13.3] Repurposing Type III CRISPR-Cas as Modular Cellular RNA Biosensors

Abstract Over the past decade, CRISPR-Cas based biosensors have emerged as sensitive, specific and programmable platforms for nucleic acid detection, with applications ranging from diagnostic tools, environmental monitoring and various applications in fundamental research. The vast majority of these biosensors are currently limited to in vitro a...

#6 [13.3] Ultrasensitive and Specific Detection of Neutralization-Correlated Serum Antibodies Via Secondary Antibody−DNA Linker-Mediated Magnetic Bead−Based Proximity Extension Assay

Abstract Sensitive, accurate, and readily deployable detection of neutralizing antibody (NAb) titers is essential for evaluating vaccine efficacy and population-level immunity. Here, we report an Antibody-DNA Linker (AND Linker) comprising a fusion of Protein A/G, a G4S flexible peptide, and duck circovirus replication initiator protein (DCV). T...

#7 [13.3] An “Off−On” Room-Temperature Phosphorescence Aptasensor for Direct Acetylcholinesterase Detection

Abstract Most acetylcholinesterase (AChE) assays quantify catalytic activity, which does not necessarily reflect protein abundance. Herein, an “off−on” room-temperature phosphorescence (RTP) aptasensor (CDs@SiO2/PEG-Apt-Q1) based on Förster resonance energy transfer (FRET) was developed for direct AChE protein detection. An AChE-binding DNA apt...

#8 [13.3] Copper-Peptide Assemblies with Self-Driven Signal Release for Electrochemical Analysis of Exosomes

Abstract Multifunctional peptides have garnered considerable attention owing to their excellent biocompatibility and unique physicochemical properties. Herein, we report an electrochemical method for the sensitive detection of exosomes based on copper-peptide assemblies with a self-driven signal release approach. In the design, an engineered his...

#9 [13.3] Interfacial Charge Regulation in Hollow CuFe2O4/Bi4O5Br2 Heterostructures for Ultrasensitive Photoelectrochemical Detection of Oxytetracycline

Abstract Antibiotic residues are increasingly being regarded as the emerging pollutants worthy of attention. Here, a hollow CuFe2O4/Bi4O5Br2 heterostructure was engineered as an aptamer-free photoactive interface for the highly sensitive determination of oxytetracycline. The hierarchical architecture combines hollow CuFe2O4 nanospheres with flow...

#10 [13.3] A cell surface-targeted MNAzyme-aptamer system for highly sensitive and visual detection of cancer cells via nucleolin activation.

Cancer has become a major disease that seriously threatens human health and life worldwide. Cytological diagnosis serves as a cornerstone for clinical oncology. However, conventional cytomorphological evaluation and immunohistochemistry (IHC) remain time-consuming and inadequate for large-scale screening and rapid on-site precision diagnosis. Co...

Methodology